Sebaceous cysts

Sebaceous cysts, also known as epidermal cysts, are small lumps or nodules under the skin filled with keratin. Sebaceous cysts are typically harmless and do not always need treatment. However, sebaceous cysts can also rupture and cause inflammation, resulting in the formation of an abscess

What is a sebaceous cyst?

Sebaceous cysts are lumps formed under the skin filled with keratin [1]. The name ‘sebaceous cyst’ has been described by many as a misnomer, as the cysts are not mainly composed of sebum [1, 2].  Sebaceous cysts usually appear on the face, neck, or torso, but can form anywhere on the skin. 

Although most sebaceous cysts are harmless, they can be at risk of developing into an abscess if the cyst becomes infected and inflamed. In very rare cases, a sebaceous cyst may also become malignant, most of these malignant growths transform into squamous cell carcinoma or basal cell carcinoma  [1, 3].

What does a sebaceous cyst look like?

A sebaceous cyst typically has the following features:

  • A round lump, beneath the skin
  • A dark punctum may be present in the centre
  • Slightly darker than your skin tone
  • Tender or warm to the touch
Sebaceous cysts are bumps filled with keratin.

Sebaceous cyst vs. Acne

A sebaceous cyst may sometimes resemble a pimple. However, unlike pimples sebaceous cysts are deeper and grow slower. The main differences between a cyst and an acne lesion is as follows:

Sebaceous cystAcne
LocationDeeper in the skinCloser to the skin’s surface
CompositionMainly keratinSebum, dead skin cells, and pus in cases of inflammatory acne
Life spanGrows slowly, may grow for monthsA single pimple may last between a few days to a few weeks
Appearance Round, dome-shaped bump, typically larger and firmer than a pimple, the bump is relatively mobileDepending on the type of acne, the lesion may appear as whiteheads, blackheads, or inflamed acne, which appears red and contains pus 

When should I be worried about a sebaceous cyst?

Sebaceous cysts are typically benign and may not require treatment. However, it is recommended to seek medical attention or treatment in case:

  • The cyst causes pain or discomfort
  • The cyst ruptures and becomes infected
  • The cyst keeps coming back 

What happens if the cyst ruptures?

A sebaceous cyst can rupture and spill its contents to the surrounding tissue, which results in inflammation and granuloma formation [2]. Common signs of a ruptured cyst are as follows:

  • Redness 
  • Swelling 
  • Tenderness
  • Pain
  • Presence of a foul-smelling, yellow discharge

When a cyst is ruptured, it is highly recommended to seek medical attention to drain the cyst to facilitate healing and prevent possible complications, such as:

  • Infection 
  • Inflammation
  • Tissue scarring 
  • Sinus tract formation 

What causes sebaceous cysts?

Sebaceous cysts originate from a follicular infundibulum, a keratin plug the blocks follicle orifice which leads to the accumulation of the keratin plug, a cyst eventually forms from the plugged keratin [1]. Most cases of sebaceous cysts are sporadic, some cysts can also be caused by genetic conditions, such as:

Sebaceous cysts are also more common in men than in women, and often develop in adulthood (30 to 40 years of age) [1].

How are sebaceous cysts diagnosed?

Sebaceous cysts diagnosis is often done with a simple physical examination by your doctor, along with assessment based on your symptoms and medical history. In rare cases, your doctor may require more tests if they require more information, in particular for large or deep seated cysts. Tests to diagnose or rule out other conditions include:

  • Imaging scans – Imaging with ultrasound scans typically helps your doctor identify the contents of the cyst, especially in large cysts where removal may be slightly more challenging. 

How are sebaceous cysts treated?

Sebaceous cysts are typically benign and do not require treatment or removal. Most cases of removal are done when the cyst is located over an area that is inconvenient or when the cyst grows too big and becomes bothersome. In rare cases, cysts can become malignant. Hence, it is highly recommended to get a medical professional to examine your skin growths or lesions before performing any removal procedure. Sebaceous cysts can be treated with the following methods:

  • Surgical excision – Surgical excision is the most common method of sebaceous cyst removal. The procedure involves using a scalpel to cut out the cyst, as well as excess skin on top of the cyst. The wound is then closed with sutures. Excision procedure also removes the cyst wall, which minimises the risk of recurrence or regrowth of the cyst. However, surgical excision may result in scars after recovery.
  • Incision and drainage – In this procedure, the doctor makes a small incision and drains the contents of the cyst. Recurrence of the cyst may occur if the cyst wall is not completely removed. This procedure is usually performed in the setting of an abscess formation.

Summary

Sebaceous cysts are normally harmless lesions on the skin. They do however have the propensity to become inflamed and develop into an abscess. However, rare cases of cancer can arise from these benign growths. Hence, it is important to consult a medical professional for removal procedures. Proper assessment and diagnosis will allow your doctor to recommend the most suitable treatment option for your sebaceous cyst.

Book a consultation with us today for a detailed diagnosis and personalised treatment plan.

Frequently Asked Questions

How do I know if I have a sebaceous cyst?

Sebaceous cysts are typically slow growing and can last for months unlike a typical pimple that may appear within a few days. If you notice a growth anywhere on your skin that seems suspicious, it is recommended to visit a doctor to get a proper examination or diagnosis. 

Can I pop a sebaceous cyst on my own?

Removing or draining the cyst on your own may inadvertently cause more damage by spreading the contents to the nearby tissue. Furthermore, squeezing or popping cysts on your own may increase the risk of scarring and recurrence. Do not pop a sebaceous cyst.

Will sebaceous cysts go away on their own?

Sebaceous cysts are not likely to go away on their own. You may leave them untreated if they do not cause any problems. However, removals should be done by a medical professional.

References

  1. Zito PM, Scharf R. Epidermoid Cyst. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499974/
  2. Hoang VT, Trinh CT, Nguyen CH, Chansomphou V, Chansomphou V, Tran TTT. Overview of epidermoid cyst. Eur J Radiol Open. 2019 Sep 5;6:291-301. doi: 10.1016/j.ejro.2019.08.003. PMID: 31516916; PMCID: PMC6732711.
  3. Kasahara R, Tajiri R, Kobayashi K, Yao M, Kitami K. Squamous Cell Carcinoma Developing from a Testicular Epidermal Cyst: A Case Report and Literature Review. Case Rep Urol. 2019 Mar 24;2019:9014301. doi: 10.1155/2019/9014301. PMID: 31019832; PMCID: PMC6451811.
  4. Wu H, Wang S, Wu L, Zheng S. A new procedure for treating a sebaceous cyst: removal of the cyst content with a laser punch and the cyst wall with a minimal postponed excision. Aesthetic Plast Surg. 2009 Jul;33(4):597-9. doi: 10.1007/s00266-009-9331-2. Epub 2009 Mar 31. PMID: 19333649; PMCID: PMC2714896.
  5. Castelanich DG, Parra Hernández LA, Chacín M. Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report. Clin Cosmet Investig Dermatol. 2024 Aug 9;17:1815-1822. doi: 10.2147/CCID.S442955. PMID: 39139846; PMCID: PMC11321352.

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